Comparison of dosimetric parameters between intensity modulated and three-dimensional conformal radiotherapy planning for adjuvant therapy of gastric cancer

Background: Adjuvant chemoradiotherapy is the standard treatment for gastric carcinoma, but optimal radiation modality remains uncertain. This study aimed to compare intensity-modulated radiotherapy (IMRT) and three-dimensional conformal (3D-CRT) in terms of dosimetry adjuvant cancer treatment. Methods: 21 patients with stage IIB-IIIC cancer, treated between January June 2021, underwent surgery followed by chemoradiation both IMRT 3D-CRT plans. Dosimetric parameters were calculated planned target volume (PTV) organs at risk (OAR). Results: Both provided comparable PTV coverage. However, significantly improved kidney sparing, reducing mean V20 value 23% (p=0.01) right 26% (p=0.02) left compared 3D-CRT. also decreased irradiated kidneys liver, as well V30 although these differences not statistically significant. The dosimetric spinal cord Conclusions: demonstrated better sparing while coverage was similar. Long-term follow-up necessary assess clinical outcomes local recurrence rates